97精品国自产拍在线观看_美日韩中文字幕_狠狠色丁香婷婷综合影院_h片欧美精品一区二区_一级毛片破过处的美女_亚洲AV有幕在线天堂动漫_无码专区白嫩少妇高潮喷水久久_皮特影院在线观看_热九九这里只有精品_亚洲综合网天天x

產(chǎn)品中心 Products
最新新聞 / News More
1
2018 - 07 - 05
doi.org/10.1038/s41586-018-0162-7基于20年的深入研究,得克薩斯大學(xué)西南醫(yī)學(xué)中心(UT Southwestern)自噬研究中心的主任Beth Levine和團隊已經(jīng)明確:細(xì)胞自噬可以延長壽命、改善健康。他們以小鼠為模型發(fā)現(xiàn),自噬水平提高的小鼠壽命更長、更健康。“具體來說,它們的壽命延長了約10%,且不太可能發(fā)生與年齡相關(guān)的自發(fā)性癌癥、心臟病等疾病?!盉eth Levine表示道。細(xì)胞自噬自噬是一種保護機制。當(dāng)細(xì)胞內(nèi)出現(xiàn)衰老的蛋白質(zhì)、損壞的細(xì)胞器等廢棄物時,自噬囊泡會將它們包裹并送至溶酶體中進行降解并得以循環(huán)利用,從而確保細(xì)胞本身的代謝需求和某些細(xì)胞器的更新。細(xì)胞自噬過程(圖片來源:華威大學(xué))20年前,Beth Levine和同事發(fā)現(xiàn)了自噬生物學(xué)過程中的一個關(guān)鍵基因beclin 1。他們還發(fā)現(xiàn),自噬對于健康而言必不可少,例如預(yù)防神經(jīng)衰退性疾病、對抗癌癥和感染。2003年,Beth Levine團隊證實,自噬關(guān)聯(lián)的基因機制對于長壽突變線蟲(long-lived mutant roundworms)的壽命延長至關(guān)重要?!皬哪且院螅P(guān)于‘自噬是延長壽命的關(guān)鍵機制’的觀點尤為火熱?!?Beth Levine解釋道,“隨著年齡增長,細(xì)胞的自噬能力會下降,這可能會導(dǎo)致衰老?!弊允裳娱L壽命然而,一個關(guān)鍵問題仍然沒有得到解答:增強自噬水平是否有益于哺乳動物的健康?換句...
2
2019 - 05 - 06
來源: 中國科學(xué)報年初,一部電視劇《都挺好》火遍全國,大結(jié)局時劇中一直讓人恨得牙癢癢的 “作爹” 蘇大強,因患上了阿爾茨海默氏癥(AD,俗稱老年癡呆癥)而成功“洗白”,惹出了不少人的眼淚。阿爾茨海默氏癥離我們并不遙遠(yuǎn),由它引發(fā)的故事也是常有耳聞,大多伴隨著無奈與辛酸。隨著全球老齡化進程的加快,愈來愈多的阿爾茨海默氏癥患者將給家屬及社會帶來沉重的負(fù)擔(dān)。根據(jù)國際阿爾茨海默氏病協(xié)會的統(tǒng)計數(shù)據(jù),2018 年全世界有 5000 萬老人患有癡呆,每 3 秒鐘,就有 1 位患者產(chǎn)生;中國是阿爾茨海默氏病的重災(zāi)區(qū),估計有 1000 萬患者。關(guān)于阿爾茨海默氏癥發(fā)病機制和治療方法的研究一直都是科研界關(guān)注的重點之一。近日,中國科學(xué)院昆明動物研究所姚永剛課題組在阿爾茨海默氏癥的治療研究上取得重要進展,該研究闡明了核受體過氧化物酶體α激動劑吉非羅齊和匹立尼酸的抗阿爾茨海默氏癥分子機制。相關(guān)論文在線發(fā)表于《自噬》(Autophagy)雜志上。誘導(dǎo)自噬,清除 Aβ作為發(fā)生在老年前期與老年期的一種常見的神經(jīng)退行性腦病,阿爾茨海默氏癥是最常見的老年癡呆類型,其發(fā)病率隨著年齡增長而顯著增加。其臨床表現(xiàn)為病人漸進性記憶喪失、認(rèn)知能力下降并伴有焦慮等其他精神相關(guān)癥狀。對于阿爾茨海默氏癥的發(fā)病機制,現(xiàn)有很多學(xué)說,其中影響最廣泛的有β- 淀粉樣蛋白(β-amyloid,Aβ)瀑布理論,認(rèn)為 Aβ的生成與清除失衡是導(dǎo)致神經(jīng)元變...
3
2019 - 09 - 05
2016年《消失的微生物》一書問世,腸道微生態(tài)研究走入大眾視野,目前全球范圍內(nèi)針對微生物與肥胖、哮喘、過敏、糖尿病、腫瘤、精神類疾病的研究正逐步開展。一、腸道微生物概況人體是由自身細(xì)胞及共生的大量微生物細(xì)胞所共同組成的復(fù)雜共生生命體。目前研究認(rèn)為人體腸道內(nèi)聚集的微生物數(shù)目可達(dá)1012~1014個,是人體自身細(xì)胞數(shù)目的10倍,微生物包含的基因數(shù)目超過987萬個,人類自身基因數(shù)只有2萬個左右,是人體自身基因數(shù)目的幾百倍,這些后天獲得的共生菌群及其所攜帶的遺傳及分子信息即可稱為微生物組。(一)人體腸道微生物是如何建立的?有研究表明,人體在出生成長過程中,主要在兩個重要的環(huán)節(jié)、以兩種不同的方式實現(xiàn)對腸道菌群的塑造。第一個環(huán)節(jié)是在分娩過程,嬰兒會從母親產(chǎn)道獲得健康的腸道菌群,剖腹產(chǎn)和孕期抗生素則會改變正常嬰兒菌群的建立。另一個環(huán)節(jié)則是出生后的哺乳及斷奶后的膳食干預(yù)。在女性乳腺中存在著乳酸菌等系列微生物,這些微生物在哺乳過程中進入并定植于嬰兒腸道。隨著哺乳期的結(jié)束,日趨豐富的膳食外源營養(yǎng)物質(zhì)則長期調(diào)節(jié)著人體腸道微生物中的的變化。(二)腸道微生物對人體健康有何影響?腸道菌群與人體互利共生,依靠人體沒有消化的食物殘渣和腸道分泌的黏液和脫落的死細(xì)胞作為營養(yǎng)來維持很高的種群水平?;钴S生長的腸道菌群會產(chǎn)生大量的活性物質(zhì),同時包括短鏈脂肪酸、維生素和抗氧化等有益健康的產(chǎn)物,以及神經(jīng)毒素、致癌物質(zhì)和免疫毒素...
聯(lián)系我們
北京照生行儀器設(shè)備有限公司
銷售熱線:010-62929079
公司總機:010-62929079
圖文傳真:010-62929277
總部地址:北京市海淀區(qū)西二旗西路熱力公司院內(nèi)泰禾文化園二層
產(chǎn)品名稱:

EVOS? FL Imaging System

上市日期: 2019-04-15
產(chǎn)品類別: EVOS

規(guī)格

Color:Transmitted Light
Data Output:BMP Files,?JPG Files,?PNG Files,?TIFF Files
Detection Method:Fluorescent
Dimensions:36 cm (14 in) (W) x 58 cm (23 in) (H) x 47 cm (19 in) (D)
Display Interface:15-inch color monitor,?Adjustable tilt
For Use With (Equipment):Fluorescence Microscope
Format:Specific Holder Attachments
Frequency:50?60 Hz
Input Voltage:100-240 VAC
Objectives:5 Objective Turret
Product Line:EVOS?
Product Size:1 each
Stage:Mechanical stage with X-Y axis fine-positioning controls
Weight:15.3 kg (33.7 lbs)


  • 產(chǎn)品描述
  • 產(chǎn)品功能
  • 產(chǎn)品參數(shù)

描述

The EVOS? FL Imaging System is a fully integrated, digital, inverted imaging system for four-color fluorescence and transmitted-light applications. It is powerful, yet easy-to-use and delivers high-definition images with exceptional convenience. The unique light cubes, sensitive camera, and precision-engineered optical system make the EVOS? FL system ideal for both demanding and routine fluorescence imaging applications.

The EVOS? FL Imaging System offers you these important advantages:

? Easy installation; no maintenance, assembly, alignment, or calibration
? For four-color fluorescence and transmitted light applications
? Five-position objective turret with front controls
? On-board software
? All-in-one design: digital camera, precision optics, LCD display, and USB storage

Fully Integrated Imaging System
The EVOS? FL system represents a new concept in transmitted light inverted microscopy. It is a fully integrated imaging system that combines precision optics, a 15' high-resolution LCD display, and a highly sensitive Sony ICX445 monochrome CCD camera (1280 x 960 pixel resolution, 1.3 Megapixels). Images are seamlessly acquired through the intuitive user interface using a mouse for easy control. Monochrome cameras are commonly used for high-performance fluorescence applications and provide the best sensitivity for detection of faint fluorescence signals. Color cameras, as on the EVOS? FL Color System, have lower fluorescence sensitivity but have the advantage of being able to differentiate structures by color in transmitted light (e.g., imaging stained tissue samples).

Compare cell imaging systems >

Versatile and Highly Configurable
The EVOS? FL system features an easily accessible 5-position objective turret and a 3-position condenser turret. The 4 fluorescence light cubes are lever-actioned for rapid and easy selection. The optical system can be configured to best meet your needs using our full range of high-quality objectives from 2x to 100x magnification. Lighting settings are automatically adjusted to match the objective magnification. The EVOS? FL system features a mechanical stage with X/Y-axis fine-positioning using control knobs conveniently located on the left side and the front of the stage. The stage accommodates EVOS? vessel holders that provide a perfect fit for most vessel types and sizes. Interchangeable stage plates accommodate most vessel types and sizes, including flasks, Petri dishes, multi-well plates, and slides.

Smart LED Illumination Technology
All EVOS? fluorescence imaging systems utilize our unique, proprietary LED light cubes. This world-leading light engine outputs remarkable intensity over a short light-path that delivers superior fluorophore excitation. Each light cube contains a precisely matched set of optical components to optimize the position, evenness, and intensity of the light beam. Digitally controlled LED light sources allow adjustment of illumination levels, dramatically improving control over photobleaching. Hard-coated filters give sharper edges and significantly higher transmission efficiencies than traditional soft-coated filters.

Integrated Software
The on-board computer makes the EVOS? FL system easy to run and use, and the intuitive, comprehensive software facilitates both image acquisition and analysis. Modules include time-lapse acquisition, manual-assist cell counting, and image review. Saved user settings work in conjunction with 'smart' controls to help increase efficiency and ease of use. Image data are saved to a USB flash drive for easy, portable data transfer or to a Windows-networked local server. Images can be saved in PNG, JPEG, BMP, and TIFF formats with a maximum captured image resolution of 1280 x 960 pixels.

These features make the EVOS? FL system ideal for both routine and demanding fluorescence imaging applications such as GFP-vector transfection efficiency analysis, routine cell and tissue culture, cell confluence determination, stem cell growth and differentiation, and developmental biology and tissue slice analyses. And the compact footprint makes it as easy to use the EVOS? FL system in a cell culture hood as on the bench.

Easy to Use and Reliable
The EVOS? FL Imaging System is plug-and-play. In addition to an exceptionally easy set-up and installation, it requires no warm-up or cool-down periods. The LED light source offers exceptional stability and durability—so you can turn the unit on and off whenever you need to image a sample. The environmentally safe mercury-free LED bulbs are rated for >50,000 hours (~17 years) of life, compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. The long life and low energy consumption translate into significantly lower operating costs compared to instruments with conventional light sources. Finally, the advanced ergonomic design of the EVOS? systems removes the strain associated with conventional microscopes, enables shared viewing, and makes moving the units easy. For extended or precision use, the EVOS? arm rest provides comfortable support.

The EVOS? imaging systems are built from the ground up to maximize performance and optimize workflow. You will be astonished at how easy it is to operate and amazed at how extraordinary your images look on-screen.

Learn more about the EVOS? FL Imaging System
Explore the entire EVOS? line of imaging systems and accessories

System Highlights
Optics: infinity-corrected optical system, RMS-threaded objectives with 45 mm parfocal distance
Illumination: adjustable intensity LED (>50,000-hour life per light cube)
Light cubes (not included): broad selection of patented standard and specialty light cubes
Common light cubes include: DAPI (Ex 360 nm/Em 447 nm), GFP (Ex 470 nm/Em 525 nm), RFP (Ex 530 nm/Em 593 nm), Texas Red? (Ex 585 nm/Em 624), Cy5 (Ex 628 nm/Em 692 nm)
Contrast methods: fluorescence and transmitted light (brightfield & phase contrast)
Objective turret: 5-position, front-mounted control
Objectives (not included): wide selection of high-quality LWD and coverslip-corrected objectives available
Condenser: 3-position turret with brightfield and phase contrast annuli
Condenser working distance: 60 mm
Stage: mechanical 'glide' stage; X-Y axis fine-positioning controls: 28.3 mm (1.11') per rotation, 110 mm x 110 mm (4.3' x 4.3') range of motion; Z-axis focusing controls: 480 μm/rotation; interchangeable vessel holders are available for most common shapes and sizes
Focus mechanism: coaxial focus knobs with tension control
Course focus: 38 mm/rev
Fine focus: 0.2mm/rev, precision 0.002 mm
LCD display: 15-inch color, 1024 x 768 pixels, adjustable tilt
Camera: Sony ICX445 monochrome CCD, 1/3' 1280 x 960 pixels, 1.3 Megapixels
Image acquisition: onboard microprocessor, built-in software for image acquisition via mouse control
Captured images: 16-bit monochrome TIFF or PNG (12-bit dynamic range); 24-bit color TIFF or PNG; jpeg, bmp, 1280 x 960 pixels
Output ports: 3 USB and 1 DVI
Power supply: AC adapter with country-specific power cords; input 100-240 V, 50-60 Hz; output 12 VDC/4.15 A
Dimensions: operating height = 57.8 cm (22.75 in); storage/transport height = 32.4 cm (12.75 in); depth = 47.0 cm (18.5 in); width = 35.5 cm (14.0 in)
Weight: 15.3 kg (33.7 lbs)?


規(guī)格

Color:Transmitted Light
Data Output:BMP Files,?JPG Files,?PNG Files,?TIFF Files
Detection Method:Fluorescent
Dimensions:36 cm (14 in) (W) x 58 cm (23 in) (H) x 47 cm (19 in) (D)
Display Interface:15-inch color monitor,?Adjustable tilt
For Use With (Equipment):Fluorescence Microscope
Format:Specific Holder Attachments
Frequency:50?60 Hz
Input Voltage:100-240 VAC
Objectives:5 Objective Turret
Product Line:EVOS?
Product Size:1 each
Stage:Mechanical stage with X-Y axis fine-positioning controls
Weight:15.3 kg (33.7 lbs)


規(guī)格

Color:Transmitted Light
Data Output:BMP Files,?JPG Files,?PNG Files,?TIFF Files
Detection Method:Fluorescent
Dimensions:36 cm (14 in) (W) x 58 cm (23 in) (H) x 47 cm (19 in) (D)
Display Interface:15-inch color monitor,?Adjustable tilt
For Use With (Equipment):Fluorescence Microscope
Format:Specific Holder Attachments
Frequency:50?60 Hz
Input Voltage:100-240 VAC
Objectives:5 Objective Turret
Product Line:EVOS?
Product Size:1 each
Stage:Mechanical stage with X-Y axis fine-positioning controls
Weight:15.3 kg (33.7 lbs)


推薦新聞
地址:中國·上?!て謻|區(qū)-浦東新區(qū)康橋路787號5號樓159室
電話:021-64396663
Copyright@ 2015-2016 北京照生行儀器設(shè)備有限公司
傳真:+86 0755-2788 8009
郵編:330520