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1
2019 - 02 - 13
日前,《分子植物》(Molecular Plant)在線發(fā)表了中國農(nóng)業(yè)科學(xué)院油料作物研究所王漢中院士團隊最新成果。該團隊在國際上首次成功克隆了農(nóng)作物種子性狀的第一個細胞質(zhì)調(diào)控基因 orf188,并揭示了該基因調(diào)控油菜種子高含油量的作用機制。該成果為油菜高含油量育種提供了新途徑,為育種過程中雜交母本的選擇提供了理論支撐,對于農(nóng)作物不同類型細胞質(zhì)的應(yīng)用具有重要的指導(dǎo)意義。含油量是油菜產(chǎn)油量最重要的構(gòu)成因子之一,隨著現(xiàn)代育種對含油量潛力的不斷挖掘,提高品種的含油量越來越困難。該團隊在油菜含油量遺傳研究的基礎(chǔ)上,從細胞質(zhì)效應(yīng)著手對含油量母體調(diào)控新機制研究取得突破,篩選到兩個對含油量具有極顯著細胞質(zhì)正負效應(yīng)的品種,鑒定出特異基因 orf188 控制細胞質(zhì)的含油量正效應(yīng),過表達該基因可以大幅度提升含油量。研究表明,orf188 為 nap(nap-like)型油菜品種所特有基因,是一個新近進化形成的嵌合基因。該團隊十余年來圍繞油菜種子性狀的母體調(diào)控進行系統(tǒng)研究,此次對細胞質(zhì)基因調(diào)控種子含油量機理的揭示,是該團隊繼發(fā)現(xiàn)角果皮發(fā)育調(diào)控種子粒重和含油量之后發(fā)現(xiàn)的又一條母體調(diào)控新途徑,進一步豐富和完善了種子性狀的母體調(diào)控理論,也為其他農(nóng)作物性狀細胞質(zhì)效應(yīng)的解析提供了借鑒。相關(guān)論文信息:DOI:10.1016/j.molp.2019.01.012來源:中國科學(xué)報轉(zhuǎn)載:生物360
2
2019 - 06 - 14
隨著技術(shù)飛速發(fā)展、醫(yī)學(xué)數(shù)據(jù)的持續(xù)擴增以及硬件設(shè)備的不斷提升,人工智能和醫(yī)療的結(jié)合方式越來越多樣化。目前AI在醫(yī)療領(lǐng)域中的落地的應(yīng)用場景主要有醫(yī)學(xué)影像、智能診療、智能導(dǎo)診、智能語音、健康管理、病例分析、醫(yī)院管理、新藥研發(fā)和醫(yī)療機器人等,其中在醫(yī)學(xué)影像中的應(yīng)用最為廣泛。一、影像醫(yī)學(xué)發(fā)展現(xiàn)狀醫(yī)學(xué)影像是醫(yī)生完成診斷的主要依據(jù),通過對影像的分析和比較,從而完成有依據(jù)的診斷。但是在實際過程中,往往會存在以下問題:(1)影像學(xué)診斷人才資源緊缺。醫(yī)療機構(gòu)普遍缺乏高水平的影像醫(yī)師,在疾病診斷時往往會發(fā)生同病異影,異病同影等情況。(2)傳統(tǒng)定性分析存在診斷誤差。醫(yī)生普遍擅長定性分析,很多微小的定量變化無法通過肉眼判斷,很難做到定量分析。(3)醫(yī)生閱片時間長。目前的影像呈現(xiàn)方式為數(shù)據(jù)和圖像,而不是最有效的信息,很大程度上限制了醫(yī)生的人工閱片速度。二、AI+醫(yī)學(xué)影像助力疾病診斷通過引入人工智能可有效解決部分問題,目前人工智能在醫(yī)學(xué)影像領(lǐng)域的應(yīng)用方向主要以下幾類:1. 影像設(shè)備的圖像重建AI可以通過算法的圖像映射技術(shù),將采集的少量信號恢復(fù)出與全采樣圖像同樣質(zhì)量的圖像,而且使用圖像重建技術(shù),可以由低劑量的CT和PET圖像重建得到高劑量質(zhì)量圖像。這樣在滿足臨床診斷需求的同時,還能夠降低輻射的風(fēng)險。2. 智能輔助診斷疾?。?)智能輔助診斷肺部疾病國內(nèi)應(yīng)用AI+CT影像最為成熟的領(lǐng)域在肺結(jié)節(jié)的識別上。AI能夠有效識...
3
2019 - 12 - 25
前瞻記憶是指個體記住未來要完成任務(wù)的能力。兒童進入學(xué)校后,前瞻記憶任務(wù)逐漸增多,對前瞻記憶能力的要求也逐漸增高。前瞻記憶任務(wù)成功的關(guān)鍵在于當個體看到線索時能主動提取并執(zhí)行意圖。前瞻記憶線索分為三種,時間線索(如周六晚上7點記得參加朋友的生日聚會)、事件線索(如路過超市記得買水果)和活動結(jié)束線索(如寫完作業(yè)記得找家長簽字)。三種線索的提取難度存在差異,這可能與其對注意資源的需求不同有關(guān)。較之正常發(fā)育的兒童,多動癥兒童在日常活動中常有注意力不集中和健忘的表現(xiàn),提示其前瞻記憶能力可能存在缺損。然而,對多動癥兒童前瞻記憶功能的研究較少,更缺乏研究直接考察多動癥兒童在三種線索條件下的前瞻記憶表現(xiàn)及其認知加工特點。因此,中國科學(xué)院心理研究所心理健康重點實驗室神經(jīng)心理和應(yīng)用認知神經(jīng)科學(xué)(NACN)實驗室陳楚僑研究組與北醫(yī)六院醫(yī)生錢英、濰坊醫(yī)學(xué)院教授王艷郁合作考察了多動癥兒童在時間、事件和活動結(jié)束線索條件下的前瞻記憶表現(xiàn)。該研究招募了28名臨床診斷的多動癥兒童和28名年齡和性別匹配的正常發(fā)育兒童,采用釣魚游戲任務(wù)(Yang, Chan, Shum, 2011)測查兒童在三種線索條件下的前瞻記憶功能。該任務(wù)采取經(jīng)典的雙任務(wù)范式,主任務(wù)要求兒童釣魚,并同時關(guān)注前瞻記憶線索,在線索出現(xiàn)時兒童需要停止釣魚并執(zhí)行前瞻記憶任務(wù)。在時間線索條件下,兒童要記得每到整分鐘就喂貓吃魚;在事件線索條件下,兒童看到特殊條...
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產(chǎn)品名稱:

Attune? NxT Acoustic Focusing Cytometer, blue/red/violet/yellow

上市日期: 2019-04-17
產(chǎn)品類別: INVITROGEN

規(guī)格

For Use With (Equipment):Attune? NxT Acoustic Focusing Cytometer
Format:Tube(s)
Green Features:Less hazardous
Laser Features:Blue Excitation Laser (488 nm),?Red Excitation Laser (638 nm),?Violet Excitation Laser (405 nm),?Yellow Laser (561 nm)
Product Line:Attune?
Product Size:1 each
Shipping Condition:Room Temperature


  • 產(chǎn)品描述
  • 產(chǎn)品功能
  • 產(chǎn)品參數(shù)

描述

The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.

? Free Attune NxT software with researcher-inspired upgrades
? New green laser option for expanded utility and fluorochrome options
? Simple push-button sample recovery function

Freakishly fast flow
The innovative combination of acoustic focusing technology coupled with traditional hydrodynamic focusing results in acquisition speeds up to 10X faster than other flow cytometers. This technology reduces the time needed to obtain results.

? True 35,000 event/sec (+10% coincidence rates)
? Maximum electronic speed of 65,000 events/sec
? Analyze small or limited samples faster than ever
? Efficiently run traditionally long assays

The Attune NxT flow cytometer is ideal for immunophenotyping and signaling studies, cell cycle analysis, detection of rare events, stem cell analysis, cancer and apoptosis studies, microbiological assays, and more.

Fit for your lab today and in the future
The instrument’s modular design provides the flexibility to meet future capability needs with a variety of upgrade options. Purchase what you need now and easily upgrade later. The small footprint of the instrument requires minimal bench space, even allowing use in a cell culture hood.

? Flexibility—1 to 4 lasers, 14 colors, and 16 parameters
? Field upgradeable—choose to add additional lasers when you decide
? Customizable band pass filters for expanded fluorochrome choices

Tune into your data
The Attune NxT Acoustic Focusing Cytometer easily runs most samples including cardiomyocytes. The system is designed with a clog-resistant syringe-driven system to push the sample with a force of up to 75 psi.?

? Flexibility in sample concentrations and sample types
? Elimination of time-consuming concentration steps with No-Wash, No-Lyse Filter Kit?
? Analysis of dilute samples, including CSF, stem cells, mouse bone marrow, mouse blood, and thin needle aspirates
? Acquisition of a high volume of samples in minimal time


規(guī)格

For Use With (Equipment):Attune? NxT Acoustic Focusing Cytometer
Format:Tube(s)
Green Features:Less hazardous
Laser Features:Blue Excitation Laser (488 nm),?Red Excitation Laser (638 nm),?Violet Excitation Laser (405 nm),?Yellow Laser (561 nm)
Product Line:Attune?
Product Size:1 each
Shipping Condition:Room Temperature


規(guī)格

For Use With (Equipment):Attune? NxT Acoustic Focusing Cytometer
Format:Tube(s)
Green Features:Less hazardous
Laser Features:Blue Excitation Laser (488 nm),?Red Excitation Laser (638 nm),?Violet Excitation Laser (405 nm),?Yellow Laser (561 nm)
Product Line:Attune?
Product Size:1 each
Shipping Condition:Room Temperature


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