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1
2018 - 06 - 22
對創(chuàng)傷經(jīng)歷的回憶會導致精神健康問題,如創(chuàng)傷后應激障礙(PTSD),這會破壞一個人的生活。據(jù)估計,當前將近三分之一的人會在他們生命中的某個時刻遭受恐懼或應激相關的障礙。如今,一項新的研究在細胞水平展示了一種療法如何能夠治療長期的創(chuàng)傷記憶。相關研究結(jié)果發(fā)表在2018年6月15日的Science期刊上,論文標題為“Reactivation of recall-induced neurons contributes to remote fear memory attenuation”。論文通信作者、瑞士洛桑聯(lián)邦理工學院(EPFL)教授Johannes Gräff說,“我們的研究結(jié)果首次揭示了讓成功治療創(chuàng)傷記憶變得可能的過程?!?#160;在治療創(chuàng)傷記憶領域,對恐懼衰減(fear attenuation)是否涉及通過新的安全記憶痕跡(memory trace of safety)或?qū)⒃嫉目謶钟洃浐圹E(memory trace of fear)重寫為安全記憶痕跡來抑制原始的恐懼記憶痕跡,人們長期以來爭論不止。圖片來自EPFL / Gräff Group。這種爭論的一部分與我們總體上還不能完全理解神經(jīng)元如何存儲記憶的事實相關。雖然這項研究取得的新發(fā)現(xiàn)不能排除這種抑制機制,但是它們首次證實了重寫創(chuàng)傷記憶在治療創(chuàng)傷記憶中的重要性。這個領域的研究重點在于理解大腦減少創(chuàng)傷記憶的能力...
2
2019 - 04 - 12
4 月 9 日,美國紐約市市長比爾 · 德 · 布拉西奧宣布,該市布魯克林區(qū)的威廉斯堡進入緊急狀態(tài),讓當?shù)孛癖娨粫r風聲鶴唳。是什么導致政府宣布這一近年罕見的公共衛(wèi)生緊急情況?答案你或許想不到,肇事者居然是為我們熟知的一種疾病——麻疹。卷土重來,美多地暴發(fā)麻疹疫情麻疹傳染性極強,多見于兒童。我國在 1965 年后進行針對性疫苗接種的推廣,這種疾病發(fā)病率逐漸減少。在美國,本已消失的麻疹病例在近些年時有出現(xiàn),今年在個別地區(qū)更是呈大暴發(fā)之勢。美國疾病控制中心(CDC)數(shù)據(jù)顯示,截至 4 月 4 日,美國 19 個州統(tǒng)計共出現(xiàn) 465 個麻疹病例,成為 2000 年以來疫情第二嚴重年份(2014 年全美病例達 667 例)。而紐約的布魯克林則成為重災區(qū),僅威廉斯堡這一社區(qū)從去年 10 月至今年 4 月 8 日就有 228 例確診病例。除紐約市外,紐約州、新澤西州、華盛頓州、密歇根州以及加州等多個地區(qū)出現(xiàn)了 3 例以上的麻疹病例。而 CDC 將一地區(qū)出現(xiàn) 3 例以上麻疹病例定義為疫情暴發(fā)。一時間,麻疹疫情成為美國公共衛(wèi)生領域最受關注的話題。推波助瀾,“反疫苗運動” 難辭其咎CDC 認為,美國的麻疹疫情與從以色列、烏克蘭和菲律賓等國來美旅客有關,這些國家正在暴發(fā)大規(guī)模麻疹疫情。而對于紐約市布魯克林區(qū)來說,麻疹疫情的暴發(fā)則要歸咎于人們的錯誤認知。一場愈演愈烈的 “反疫苗運動”,...
3
2019 - 08 - 23
2019年8月23日訊 /生物谷BIOON /——2019年6月,歐洲大部分地區(qū)遭遇了早期熱浪,法國的氣溫達到了創(chuàng)紀錄的46攝氏度(115華氏度)。熱浪的特點是在幾天幾夜持續(xù)高溫。它們對我們的日常生活有重要的影響--我們感到過熱和疲勞。當熱浪來襲時,許多政府會啟動一項'熱行動計劃',建議受影響的人多喝水,避免劇烈運動,保持涼爽。如果不這樣做,就有中暑的風險,而中暑有可能危及生命。但是,人體究竟是如何應對如此極端的溫度的呢?為什么高溫如此危險呢?哪些器官受到影響,什么時候情況會變得更糟?圖片來源:http://cn.bing.com保持涼爽人體的核心溫度通常在36到38攝氏度之間波動(97到99華氏度)。在這個溫度范圍內(nèi),生化反應可以正常進行,這對細胞和器官的正常功能至關重要。人類的身體也能很好地應對各種可能威脅其核心溫度的環(huán)境條件。當核心溫度偏離正常范圍時,身體就會啟動生理反應,使溫度恢復正常。這種溫度調(diào)節(jié)反應相當于你家的恒溫器;一旦內(nèi)部溫度偏離理想溫度,加熱或冷卻系統(tǒng)就會被激活,回到理想溫度。在人體中,這個恒溫器位于我們大腦的底部,一個叫做下丘腦的區(qū)域。位于我們皮膚、肌肉和其他器官的溫度傳感器提供的信息被分析,必要時,啟動生理反應。對溫度升高的第一個也是最重要的反應是通過我們身體的皮膚和四肢,如手和腳散熱。我們開始產(chǎn)生汗液,汗液會在皮膚上蒸發(fā),在這個過程中散熱。這...
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型號:
時間: 2019 - 04 - 15
描述This achromat objective is ideal for general applications. This is a coverslip-corrected objective that is optimized for imaging through #1.5 coverslips. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of this EVOS® objective:? Magnification: 50X? Numerical Aperture: 0.95? Working Distance:...
產(chǎn)品名稱: EVOS? M7000 Imaging System
型號:
時間: 2019 - 04 - 15
描述The EVOS M7000 Imaging System is a high-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system. It was developed to meet today’s expectations for image quality, user interface interactions, data generation speed and flexibility, and end-user value. The powerful and time-saving acquisition tools with enhanced autofocus algorithms and automated routines for microwell plate assays, time-lapse live cell imaging, area scanning in time lapse and Z-sta...
產(chǎn)品名稱: EVOS? FL Imaging System
型號:
時間: 2019 - 04 - 15
描述The EVOS® FL Imaging System is a fully integrated, digital, inverted imaging system for four-color fluorescence and transmitted-light applications. It is powerful, yet easy-to-use and delivers high-definition images with exceptional convenience. The unique light cubes, sensitive camera, and precision-engineered optical system make the EVOS® FL system ideal for both demanding and routine fluorescence imaging applications.The EVOS® FL Imaging System offers you these important ad...
產(chǎn)品名稱: EVOS? Onstage Master Plate
型號:
時間: 2019 - 04 - 15
描述The EVOS® Onstage Master Plate is part of the EVOS® Onstage Incubator and holds the EVOS® Onstage Vessel Holder. The EVOS® Onstage Incubator is an environmental chamber designed specifically for use with the EVOS® FL Auto Imaging System. This master plate plus vessel holder design, with vessel holders available that accommodate various types of cell culture vessels, provides flexibility in your approach to extended time-lapse imaging experiments under precisely co...
型號:
時間: 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates two 25-mL T-flasks. With ...
型號:
時間: 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates multi-well plates (dimensi...
型號:
時間: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder securely holds two 25 x 75 mm standard or chamber microscope slides and is specific for the automated stage of the EVOS® FL Auto Imaging System. It is just one of many easy-to-change vessel holders and stage plates available for this instrument plat...
型號:
時間: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Greiner/BD T-25 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ...
產(chǎn)品名稱: EVOS? Vessel Holder, universal
型號:
時間: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder has a 25.4 mm opening and accommodates most vessel types. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samp...
型號:
時間: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Greiner T-75 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ves...
型號:
時間: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates a hemocytometer. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of vessel hol...
型號:
時間: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Nunc® T-75 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ...
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