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2022 - 03 - 17
來(lái)源：生物谷 2021-03-14 00:052021年3月12日訊/生物谷BIOON/--汽水是一種備受歡迎的飲料，在全世界被廣泛消費(fèi)。食品制造商為了豐富汽水的口味，開(kāi)發(fā)了各種汽水飲品。其中不乏含糖飲料。我們知道，食品中的添加糖會(huì)給健康帶來(lái)負(fù)面影響，比如增加心血管疾病、肥胖和糖尿病風(fēng)險(xiǎn)等。那么，飲用含糖汽水對(duì)乳腺癌患者的影響如何呢？近日，來(lái)自美國(guó)布法羅大學(xué)的一項(xiàng)新研究表明，乳腺癌患者經(jīng)常飲用含糖汽水會(huì)增加全死亡的風(fēng)險(xiǎn)，尤其是因乳腺癌死亡的風(fēng)險(xiǎn)。與從不或很少喝含糖汽水的女性相比，每周喝五次或以上含糖汽水的女性其全因死亡率要高出62%，而死于乳腺癌的可能性要高出85%。相關(guān)研究結(jié)果于3月2日發(fā)表在美國(guó)癌癥研究協(xié)會(huì)的Cancer Epidemiology Biomarkers & Prevention期刊上，標(biāo)題為Sugar-Sweetened Soda Consumption and Total and Breast Cancer Mortality: The Western New York Exposures and Breast Cancer (WEB) Study。該研究的第一作者、布法羅大學(xué)公共衛(wèi)生和健康職業(yè)學(xué)院流行病學(xué)和環(huán)境衛(wèi)生系的博士生Nadia Koyratty說(shuō)，關(guān)于汽水和乳腺癌的研究是非常新穎的話題。因?yàn)槿橄侔┓浅Ｆ毡?，關(guān)于生活方式選擇的建議對(duì)乳腺癌幸存者...
5
2019 - 01 - 07
2019年1月7日 訊 /生物谷BIOON/ --誘發(fā)癌癥有很多遺傳原因，比如有些突變會(huì)遺傳自父母，而其它則是后天獲得性的突變，比如因外界因素或DNA復(fù)制的錯(cuò)誤導(dǎo)致等，大規(guī)模的基因組測(cè)序在識(shí)別因體細(xì)胞突變所誘發(fā)的癌癥上取得了一系列研究成果，但這種技術(shù)卻無(wú)法有效識(shí)別因遺傳性突變所誘發(fā)的癌癥，而且識(shí)別這些遺傳突變的主要來(lái)源仍然是基于家族性的研究。圖片來(lái)源：iran-daily.com近日，一項(xiàng)刊登在國(guó)際雜志Nature Communications上的研究報(bào)告中，來(lái)自巴塞羅那基因組研究中心的科學(xué)家們通過(guò)研究開(kāi)發(fā)了一種新型的統(tǒng)計(jì)學(xué)方法，其能夠從腫瘤測(cè)序數(shù)據(jù)中鑒別出癌癥易感性基因；該方法使用了一種古老的想法，即癌基因通常需要“兩次擊打”（two hits）才能夠致癌，研究者表示，這種方法能幫助他們從當(dāng)前癌癥基因組數(shù)據(jù)庫(kù)中系統(tǒng)性地鑒別出相關(guān)的基因。研究者將這種統(tǒng)計(jì)學(xué)方法命名為“ALFRED”，目前該技術(shù)已經(jīng)鑒別出了13個(gè)候選的癌癥易感性基因，其中10個(gè)基因都是此前并未發(fā)現(xiàn)的；Ben Lehner博士說(shuō)道，我們對(duì)30種不同類型的腫瘤患者進(jìn)行研究，將這種方法應(yīng)用于1萬(wàn)多名患者的基因組序列中，最終鑒別出了已知的和一些新型的可能性癌癥易感基因，這些基因有可能會(huì)誘發(fā)一定的患癌風(fēng)險(xiǎn)。研究者指出，新型的癌癥易感基因或許在多種類型癌癥的發(fā)生上扮演著關(guān)鍵角色，比如，其與14%的卵巢腫瘤、1%的乳腺癌等癌癥直接...
6
2019 - 05 - 27
5月24日，記者從中國(guó)農(nóng)業(yè)科學(xué)院科研進(jìn)展通報(bào)會(huì)上獲悉，由中國(guó)農(nóng)業(yè)科學(xué)院哈爾濱獸醫(yī)研究所（以下稱哈獸研）自主研發(fā)的非洲豬瘟疫苗取得了階段性成果，實(shí)驗(yàn)室研究結(jié)果表明，具有良好的生物安全性和免疫保護(hù)效果。非洲豬瘟疫苗科研攻關(guān)負(fù)責(zé)人介紹，目前在非洲豬瘟疫苗創(chuàng)制階段主要取得五項(xiàng)進(jìn)展：一是分離我國(guó)第一株非洲豬瘟病毒。建立了病毒細(xì)胞分離及培養(yǎng)系統(tǒng)和動(dòng)物感染模型，對(duì)其感染性、致病力和傳播能力等生物學(xué)特性進(jìn)行了較為系統(tǒng)的研究，并揭示了我國(guó)非洲豬瘟流行毒株的基因組特點(diǎn)和進(jìn)化關(guān)系。二是創(chuàng)制了非洲豬瘟候選疫苗，實(shí)驗(yàn)室階段研究證明其中兩個(gè)候選疫苗株具有良好的生物安全性和免疫保護(hù)效果。三是兩種候選疫苗株體外和體內(nèi)遺傳穩(wěn)定性強(qiáng)。分別將兩種候選疫苗株在體外原代細(xì)胞中連續(xù)傳代，其生物學(xué)特性及基因組序列無(wú)明顯改變，豬體內(nèi)連續(xù)傳代，也未發(fā)現(xiàn)明顯毒力返強(qiáng)現(xiàn)象。四是明確了最小保護(hù)接種劑量，證明大劑量和重復(fù)劑量接種安全。五是臨床前中試產(chǎn)品工藝研究初步完成。目前已建立兩種候選疫苗的生產(chǎn)種子庫(kù)，初步完成了疫苗生產(chǎn)種子批純凈性及外源病毒檢驗(yàn)，初步優(yōu)化了候選疫苗的細(xì)胞培養(yǎng)及凍干工藝。非洲豬瘟疫情發(fā)生后，黨中央、國(guó)務(wù)院高度重視疫情防控科研攻關(guān)。中國(guó)農(nóng)科院科技局局長(zhǎng)任天志介紹，按照農(nóng)業(yè)農(nóng)村部黨組統(tǒng)一部署，中國(guó)農(nóng)科院將非洲豬瘟防控作為服務(wù)國(guó)家戰(zhàn)略需求的重大科研攻關(guān)任務(wù)，集聚優(yōu)勢(shì)資源，第一時(shí)間組建非洲豬瘟防控科技攻關(guān)項(xiàng)目組，以哈爾濱獸醫(yī)研究...
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時(shí)間： 2019 - 04 - 17
描述The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.? Free Attune NxT software with researcher-inspired upgrades? New green laser option for expanded utility and fluorochrome options? Simple push...
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時(shí)間： 2019 - 04 - 17
描述The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.? Free Attune NxT software with researcher-inspired upgrades? New green laser option for expanded utility and fluorochrome options? Simple push...
產(chǎn)品名稱： 7-AAD (7-Aminoactinomycin D)
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時(shí)間： 2019 - 04 - 17
描述7-aminoactinomycin D (7-AAD) is a fluorescent intercalator that undergoes a spectral shift upon association with DNA. 7-AAD/DNA complexes can be excited by the 488 nm laser and has an emission maxima of 647 nm, making this nucleic acid stain useful for multicolor fluorescence microscopy and flow cytometry. 7-AAD appears to be generally excluded from live cells, but can be used with cells that have been fixed and permeabilized. 7-AAD has been used for cell cycle analysis by flow cytometry....
產(chǎn)品名稱： Dynabeads? CD45
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時(shí)間： 2019 - 04 - 17
DescriptionDynabeads® CD45 are superparamagnetic beads covalently coupled to anti-human CD45 antibody that enable isolation or depletion of CD45+ leucocytes directly from whole blood, buffy coat, or MNC suspensions. Dynabeads® CD45 can also be used to enrich epithelial tumor cells. The CD45 antigen is weakly expressed on myeloid cells. To efficiently deplete or isolate all leucocytes including myeloid cells, use Dynabeads® CD15 (Cat. No. 11137D) in combination with Dynabeads®...
型號(hào)：
時(shí)間： 2019 - 04 - 15
描述This achromat objective is ideal for general applications. This is a coverslip-corrected objective that is optimized for imaging through #1.5 coverslips. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of this EVOS® objective:? Magnification: 50X? Numerical Aperture: 0.95? Working Distance:...
產(chǎn)品名稱： EVOS? M7000 Imaging System
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時(shí)間： 2019 - 04 - 15
描述The EVOS M7000 Imaging System is a high-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system. It was developed to meet today’s expectations for image quality, user interface interactions, data generation speed and flexibility, and end-user value. The powerful and time-saving acquisition tools with enhanced autofocus algorithms and automated routines for microwell plate assays, time-lapse live cell imaging, area scanning in time lapse and Z-sta...
產(chǎn)品名稱： EVOS? FL Imaging System
型號(hào)：
時(shí)間： 2019 - 04 - 15
描述The EVOS® FL Imaging System is a fully integrated, digital, inverted imaging system for four-color fluorescence and transmitted-light applications. It is powerful, yet easy-to-use and delivers high-definition images with exceptional convenience. The unique light cubes, sensitive camera, and precision-engineered optical system make the EVOS® FL system ideal for both demanding and routine fluorescence imaging applications.The EVOS® FL Imaging System offers you these important ad...
產(chǎn)品名稱： EVOS? Onstage Master Plate
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時(shí)間： 2019 - 04 - 15
描述The EVOS® Onstage Master Plate is part of the EVOS® Onstage Incubator and holds the EVOS® Onstage Vessel Holder. The EVOS® Onstage Incubator is an environmental chamber designed specifically for use with the EVOS® FL Auto Imaging System. This master plate plus vessel holder design, with vessel holders available that accommodate various types of cell culture vessels, provides flexibility in your approach to extended time-lapse imaging experiments under precisely co...
型號(hào)：
時(shí)間： 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates two 25-mL T-flasks. With ...
型號(hào)：
時(shí)間： 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates multi-well plates (dimensi...
型號(hào)：
時(shí)間： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder securely holds two 25 x 75 mm standard or chamber microscope slides and is specific for the automated stage of the EVOS® FL Auto Imaging System. It is just one of many easy-to-change vessel holders and stage plates available for this instrument plat...
型號(hào)：
時(shí)間： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Greiner/BD T-25 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ...
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